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Common adverse effects include nausea, vomiting, diarrhoea, and a modest increase in heart rate, consistent with the GLP-1 receptor agonist class
Patients often notice they can comfortably adhere to smaller portions, avoid excessive snacking, and make healthier choices without feeling deprived
It takes 5-6 half-lives for the drug to clear from the system
A 7-fold increase in bioavailability means that a 500 mcg oral dose of the arginate form could deliver the equivalent systemic exposure of approximately 3,500 mcg of the acetate form taken orally
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